Wir haben zuvor einen transgenen Mausstamm (LSL-TβRI CA ) erzeugt, der einen Cre-induzierbaren konstitutiv aktiven TGFβ-Typ-I-Rezeptor enthält ( Bartholin L. et al. 2008. Generation of mice with conditionally enabled transforming growth factor beta signaling through the TbetaRI/ALK5 Rezeptor, GENESIS). Die Transgenexpression hängt von der Exzision eines floxed-transcriptional STOP (LSL, Lox-STOP-Lox) ab, das sich stromaufwärts der TβRI CA befindetkodierende Sequenz. Um die korrekte […]
WeiterlesenPolyklonaler Kaninchen-Antikörper Anti-CRBN
Cereblon (CRBN) was originally identified as a protein involved in human intellectual disability and has recently been recognized as a negative regulator of adenosine monophosphate-activated protein kinase (AMPK) in vivo and in vitro . Here we present results showing that CRBN can effectively regulate new protein synthesis via the mammalian target rapamycin (mTOR) signaling pathway, […]
WeiterlesenFötales Rinderserum (FBS), Premium
Cell culture professionals around the world are discovering how well their cells thrive on nutritionally superior VWR Life Science Seradigm sera, making them the fastest growing global sera brand on the market! Seradigm’s unique collection and manufacturing techniques preserve more of the naturally occurring growth factors in sera that cells need to thrive. Our proven […]
WeiterlesenAnigen Rapid FIV Ab/FeLV Ag Testkit
Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) infections occur in cats worldwide. Both infections are associated with a variety of clinical symptoms and can affect quality of life and longevity. This document is an update of the 2008 Feline Retroviral Management Guidelines issued by the American Association of Feline Practitioners and represents the […]
WeiterlesenMouse Anti-Chick Type I Collagen IgG Antibody Assay Kit, TMB
Epstein-Barr virus (EBV) belongs to the Herpesviridae family and is considered to be one of the most prevalent viruses affecting humans. It is estimated that more than 90% of the world’s population is seropositive for EBV. After infection, EBV establishes a latency period in B lymphocytes, allowing for subsequent reactivation and recurrent infection. During these […]
WeiterlesenRainbow Linear Calibration Particles
The use of flow cytometry to analyze small particles has been practiced for several decades. More recently, due to the increased sensitivity of conventional and commercially available flow cytometers, along with the growing interest in other small particles, such as e.g. B. extracellular vesicles, increasingly used. Despite an increasing use of small particle flow cytometry, the […]
WeiterlesenCarboxylic Magnetic Particles
Magnetische Partikel (MPs) sind für viele verschiedene Anwendungen in den Bereichen Biotechnologie, Biomedizin und Umweltsanierung von großem Interesse. Um verschiedenen Anwendungen Rechnung zu tragen, ist die größenkontrollierte Synthese von MPs von besonderem Interesse. Hier berichten wir über eine einfache Synthese von MPs im Bereich von Nano- bis Mikrogröße (23 nm bis 1,2 μm). Insbesondere wurde die Partikelgröße von […]
WeiterlesenNATtrol Respiratory Validation Panel (RVP) (Qualitative) (13 X 0.2 mL)
Sensitive, high-throughput molecular detection assays are essential during the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The vast majority of SARS-CoV-2 molecular assays use nasopharyngeal swabs (NPS) or oropharyngeal swabs (OPS) collected from suspected individuals. However, using NPS or OPS as probes has obvious disadvantages, e.g. B. […]
WeiterlesenMonophosphoryl lipid A (MPLA) (Synthetic, TLR4/Th1) vaccine adjuvant
Rabies, one of the world’s most threatening zoonoses, causes a deadly disease of the central nervous system (CNS). Until now, vaccination with rabies vaccines has been the most effective measure for the prevention and control of this disease. Currently, inactivated rabies vaccines are widely used in humans and domestic animals. However, the humoral immune responses […]
WeiterlesenExtended Synaptotagmin-1 (ESYT1) Antibody
Cystic fibrosis (CF) is the most common life-limiting (median age at death ~28 years) rare disease, affecting ~32,000 people in Europe (~85,000 worldwide). This inherited disorder results from mutations in the gene encoding the CF transmembrane conductance regulator (CFTR), an epithelial chloride (Cl – ) and bicarbonate (HCO 3 – ) anion channel. Despite symptomatic therapies, […]
Weiterlesen