Rabies, one of the world’s most threatening zoonoses, causes a deadly disease of the central nervous system (CNS). Until now, vaccination with rabies vaccines has been the most effective measure for the prevention and control of this disease. Currently, inactivated rabies vaccines are widely used in humans and domestic animals. However, the humoral immune responses […]
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Lentiviral Interleukin-10 Gene Therapy Preserves Fine Motor Circuitry and Function After a Cervical Spinal Cord Injury in Male and Female Mice
In mammals, spinal wire accidents usually end in muscle paralysis by way of the apoptosis of decrease motor neurons and denervation of neuromuscular junctions. Earlier analysis exhibits that the inflammatory response to a spinal wire damage may cause further tissue injury after the preliminary trauma. To modulate this inflammatory response, we delivered lentiviral anti-inflammatory interleukin-10, […]
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